CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 442 enrolled
Drug / intervention
Ranolazine +5 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01555164
NCT01555164Phase 3Completed

A Phase 3, Randomized, Double-blind, Placebo-controlled, Parallel Group Study to Evaluate the Efficacy and Safety of Ranolazine When Added to Metformin in Subjects With Type 2 Diabetes Mellitus

Gilead Sciences·interventional·Posted Mar 15, 2012·Updated Sep 23, 2014

In Brief

A Phase 3 clinical trial evaluating Ranolazine, Placebo to match ranolazine, and 4 other interventions for Type 2 Diabetes Mellitus. Completed, enrolled 442 participants across 146 sites in 11 countries.

Detailed Summary

This is a randomized, double-blind, placebo-controlled, parallel-group, multicenter study to determine the effect of ranolazine when added to metformin on glycemic control in adults with type 2 diabetes mellitus (T2DM) who are inadequately controlled despite current treatment with stable metformin therapy in addition to diet and exercise.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesCanada, Czechia, Hungary, India, Israel, Mexico, Poland, Russia, South Africa, Ukraine, United States
Collaborators--

Timeline

Phase 3CompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedMar 15, 2012
Enrollment StartJun 1, 2012
Primary CompletionSep 1, 2013
Study CompletionOct 1, 2013
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 14.3 years ago

Interventions

Ranolazinedrug

Ranolazine tablet(s) administered orally

Placebo to match ranolazinedrug

Placebo to match ranolazine for the duration of the study

Metformindrug

Metformin tablet(s) administered orally once daily

Placebo to match metformindrug

Placebo to match metformin for the duration of the study

Dietbehavioral

Participants are instructed to continue the diet regimen prescribed by their physician.

Exercisebehavioral

Participants are instructed to continue the exercise regimen prescribed by their physician.