CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 65 enrolled
Drug / intervention
Sodium fluoride / silica and carbopol, 0.5g +3 moredrug
Likely dose
Sodium fluoride / silica and carbopol, 0.5gfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01563172
NCT01563172Phase 4Completed
CompareCT.gov

A Study to Measure the Effect of Dentifrice Usage Regime on Delivery and Efficacy of Fluoride Using an In Situ Caries Model

GlaxoSmithKline·interventional·Posted Mar 26, 2012·Updated Feb 7, 2018

In Brief

A Phase 4 clinical trial evaluating Sodium fluoride / silica and carbopol, 0.5g, Sodium fluoride / silica and carbopol, 1.5g, and 1 other intervention for Dental Caries. Completed, enrolled 65 participants across 1 site.

Detailed Summary

This study will evaluate and compare the effect of the amount of toothpaste used and brushing time on enamel strengthening (percent of surface microhardness recovery, % SMHR) and enamel fluoride uptake (EFU).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDental Caries
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
200920102011201220132014201520162017201820192020202120222023202420252026
First PostedMar 26, 2012
Enrollment StartJan 1, 2009
Primary CompletionJun 1, 2009
TodayJul 2, 2026
Enrollment to primary: 5 monthsPosted 14.3 years ago

Interventions

Sodium fluoride / silica and carbopol, 0.5gdrug

Dentifrice containing 1150 parts per million (ppm) fluoride as sodium fluoride / silica and 0.4% carbopol

Sodium fluoride / silica and carbopol, 1.5gdrug

Dentifrice containing 1150 ppm fluoride as sodium fluoride / silica and 0.4% carbopol

Sodium fluoride / silica and carbopol, 1.5gdrug

Dentifrice containing 250 ppm fluoride as sodium fluoride / silica and 0.4% carbopol

Fluoride free dentifriceother

A non fluoride dentifrice was given to participants of each arm at washout period