CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 140 enrolled
Drug / intervention
PT001 MDI +2 moredrug
Likely dose
Tiotropium Bromide 18 µgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01566773
NCT01566773Phase 2Completed

A Randomized, Double Blind (Test Products and Placebo), Chronic Dosing (14 Days), Four Period, Eight Treatment, Placebo-Controlled, Incomplete Block, Cross Over, Multi Center Study to Assess Efficacy and Safety of Six Doses of PT001 in Patients With Moderate to Severe COPD, Compared With Spiriva® Handihaler® (Tiotropium Bromide, Open Label) as An Active Control

Pearl Therapeutics, Inc.·interventional·Posted Mar 29, 2012·Updated Oct 12, 2017

In Brief

A Phase 2 clinical trial evaluating PT001 MDI, Tiotropium Bromide, and 1 other intervention for Chronic Obstructive Pulmonary Disease. Completed, enrolled 140 participants across 10 sites.

Detailed Summary

The overall objective of this study is to determine an optimal dose and dosing regimen of PT001 MDI for further evaluation in later stage studies.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedMar 29, 2012
Enrollment StartMar 1, 2012
Primary CompletionAug 1, 2012
TodayJul 2, 2026
Enrollment to primary: 5 monthsPosted 14.3 years ago

Interventions

PT001 MDIdrug

Administered as two puffs BID for 14 days

Tiotropium Bromidedrug

Taken as 1 capsule containing 18 µg of tiotropium via the Handihaler DPI

PT001 Placebo MDIdrug