CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 18 enrolled
Drug / intervention
Oral Antibiotic and Oral Rinse +1 moredrug
Likely dose
Oral Antibiotic and Oral Rinse 500 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01568944
NCT01568944N/ACompleted
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Peripheral Blood Dendritic Cells and Periodontitis

Augusta University·interventional·Posted Apr 2, 2012·Updated May 12, 2020

In Brief

A clinical study evaluating Oral Antibiotic and Oral Rinse and Standard Treatment for Chronic Periodontitis. Completed, enrolled 18 participants across 1 site.

Detailed Summary

The investigators hypothesize that blood dendritic cells harbor pathogens from the oral cavity in chronic periodontitis and disseminate these pathogens to atherosclerotic plaques.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsChronic Periodontitis
CountriesUnited States
CollaboratorsNational Institute of Dental and Craniofacial Research (NIDCR)

Timeline

N/ACompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedApr 2, 2012
Enrollment StartMar 1, 2012
Primary CompletionSep 1, 2014
TodayJul 2, 2026
Enrollment to primary: 2.5 yearsPosted 14.3 years ago

Interventions

Oral Antibiotic and Oral Rinsedrug

PO Amoxicillin in 500 mg / Metronidazole 250 mg of each TID for 8 days plus 2 ounces of 0.12% chlorhexidine mouthrinse used BID

Standard Treatmentprocedure

Full mouth scaling and root planing using hand instrumentation (curettes) and ultrasonic scalers