At a glance
ClinicalIndex Comparison RecordN/ACompleted· 49 enrolled
Drug / intervention
MRI scanning +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Investigation of Brain Nitrogen in Partial Ornithine Transcarbamylase Deficiency (OTCD) Using 1 H MRS, DTI, and fMRI
In Brief
An observational study evaluating MRI scanning and Cognitive testing for Ornithine Transcarbamylase Deficiency. Completed, enrolled 49 participants.
Detailed Summary
The purpose of this study is to use various types of MRI and cognitive testing to evaluate changes in the brain and cognitive function that occur in subjects with ornithine transcarbamylase deficiency (OTCD) relative to healthy individuals
Study Details
Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsOrnithine Transcarbamylase Deficiency
Countries--
CollaboratorsChildren's National Research Institute
Timeline
N/ACompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
Enrollment StartSep 2010
First PostedApr 2012
Primary CompletionAug 2014
TodayJul 2026
First PostedApr 3, 2012
Enrollment StartSep 1, 2010
Primary CompletionAug 1, 2014
TodayJul 2, 2026
Enrollment to primary: 3.9 yearsPosted 14.2 years ago
Interventions
MRI scanningother
1H MRS, DTI, FMRI
Cognitive testingbehavioral
Behavioral testing