CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 20 enrolled
Drug / intervention
dexamethasone intravitreal implant +1 moredrug
Likely dose
dexamethasone intravitreal implant 0.7 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01571232
NCT01571232Phase 2Completed

Ozurdex for Treatment of Recalcitrant Diabetic Macular Edema.

Retina Macula Institute·interventional·Posted Apr 5, 2012·Updated Mar 30, 2021

In Brief

A Phase 2 clinical trial evaluating dexamethasone intravitreal implant and intravitreal bevacizumab for Diabetic Macular Edema and 2 related conditions. Completed, enrolled 20 participants across 1 site.

Detailed Summary

The purpose of this study is to test the efficacy of an 0.7 mg intravitreal dexamethasone implant (Ozurdex®) on macular leakage and visual acuity for patients with recalcitrant diabetic macular edema.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
CollaboratorsAllergan

Timeline

Phase 2CompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedApr 5, 2012
Enrollment StartApr 1, 2012
Primary CompletionFeb 1, 2014
Study CompletionMar 1, 2015
TodayJul 2, 2026
Enrollment to primary: 1.8 yearsPosted 14.2 years ago

Interventions

dexamethasone intravitreal implantdrug

Ozurdex, 0.7 mg intravitreal dexamethasone implant, given at initial visit and at month 4 (visit 5)

intravitreal bevacizumabdrug

Avastin, 1.25 mg intravitreal bevacizumab, given at initial visit and Q1month for a total of 5 treatments.