CI

At a glance

ClinicalIndex Comparison Record
Early Ph 1Completed· 83 enrolled
Drug / intervention
Active social engagement group +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01571427
NCT01571427Early Ph 1Completed

Conversational Engagement as a Means to Delay Alzheimer's Disease Onset

Oregon Health and Science University·interventional·Posted Apr 5, 2012·Updated Feb 5, 2020

In Brief

A Early Phase 1 clinical trial evaluating Active social engagement group and Control group for Mild Cognitive Impairment and Cognitive Change. Completed, enrolled 83 participants across 1 site.

Detailed Summary

Past epidemiological studies have demonstrated that larger social networks, or more frequent social interactions, could have potential protective effects on the incidence of Alzheimer's Disease (AD). However, in those studies, indicators of social interactions were often broad, and included distinct elements that affected cognition and overall health. This project will examine whether conversation-based cognitive stimulation has positive effects on domain-specific cognitive functions among the elderly. Face-to-face communication will be conducted through the use of personal computers, webcams, and user-friendly simple interactive Internet programs to allow participants to have social engagement while staying at their home and also for the cost effective execution of the study.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Early Ph 1CompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedApr 5, 2012
Enrollment StartFeb 1, 2012
Primary CompletionSep 1, 2013
TodayJul 2, 2026
Enrollment to primary: 1.6 yearsPosted 14.2 years ago

Interventions

Active social engagement groupbehavioral

Engage in 30 minutes conversation daily using internet/webcam, 5 days per week for 6 weeks, tracking of daily conversational amount outside of the trial by using a digital recording device, lasting effects will be assessed at the 3rd and 6th month after completion of the intervention

Control groupbehavioral

No active intervention, weekly phone calls by interviewer to complete health/social engagement monitoring survey, tracking of daily conversational amount by using a digital recording device. Participants will be reassessed at the 3rd and 6th month after completion of the intervention.