CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 74 enrolled
Drug / intervention
Sodium bicarbonate +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01574157
NCT01574157N/ACompleted
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Investigations of the Optimum Serum Bicarbonate Level in Renal Disease

VA Office of Research and Development·interventional·Posted Apr 10, 2012·Updated Aug 28, 2019

In Brief

A clinical study evaluating Sodium bicarbonate and Placebo for Chronic Renal Insufficiency and Diabetes Mellitus. Completed, enrolled 74 participants across 1 site.

Detailed Summary

The purpose of this study is to see if treatment with sodium bicarbonate will lower urine levels of proteins that are indicators of kidney damage in people with diabetes who also have chronic kidney disease.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsChronic Renal Insufficiency, Diabetes Mellitus
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedApr 10, 2012
Enrollment StartNov 5, 2012
Primary CompletionMay 1, 2018
TodayJul 2, 2026
Enrollment to primary: 5.5 yearsPosted 14.2 years ago

Interventions

Sodium bicarbonatedrug

Participants will receive 0.5 meq of sodium bicarbonate per 1 kilogram of lean body weight daily. The total amount will be divided into twice daily doses.

Placebodrug

Participants will receive an identical number of placebo tablets had they been assigned to the intervention. Placebo will be divided into twice daily doses and receive this for six months.