CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 7,180 enrolled
Drug / intervention
Romosozumab +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01575834
NCT01575834Phase 3Completed

A Multicenter, International, Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Assess the Efficacy and Safety of Romosozumab Treatment in Postmenopausal Women With Osteoporosis

Amgen·interventional·Posted Apr 12, 2012·Updated Aug 28, 2024

In Brief

A Phase 3 clinical trial evaluating Romosozumab, Placebo, and 1 other intervention for Postmenopausal Osteoporosis. Completed, enrolled 7,180 participants across 218 sites in 24 countries.

Detailed Summary

The purpose of this study is to determine if treatment with romosozumab is effective in preventing fractures in women with postmenopausal osteoporosis

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesArgentina, Australia, Belgium, Brazil, Canada, Colombia, Czechia, Denmark, Dominican Republic, Estonia, Germany, Hungary, India, Japan, Latvia, Lithuania, Mexico, New Zealand, Poland, Romania, Spain, Switzerland, United Kingdom, United States
Collaborators--

Timeline

Phase 3CompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedApr 12, 2012
Enrollment StartMar 15, 2012
Primary CompletionDec 14, 2015
Study CompletionDec 28, 2016
TodayJul 2, 2026
Enrollment to primary: 3.7 yearsPosted 14.2 years ago

Interventions

Romosozumabdrug

Administered by subcutaneous injection once a month (QM)

Placebodrug

Administered by subcutaneous injection once a month (QM)

Denosumabdrug

Administered by subcutaneous injection once every 6 months (Q6M)