CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 70 enrolled
Drug / intervention
Omeprazole +4 moredrug
Likely dose
Omeprazole 20 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01593592
NCT01593592N/ACompleted

Lactobacillus Reuteri in Management of Helicobacter Pylori Infection in Dyspeptic Patients: a Double Blind Placebo Controlled Randomized Clinical Trial

Zagazig University·interventional·Posted May 8, 2012·Updated Aug 17, 2015

In Brief

A clinical study evaluating Lactobacillus reuteri, Placebo, and 3 other interventions for Helicobacter Pylori Infection. Completed, enrolled 70 participants across 1 site.

Detailed Summary

Addition of L. reuteri to the standard triple therapy improves H. Pylori treatment outcomes.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesEgypt
CollaboratorsBioGaia AB

Timeline

N/ACompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedMay 8, 2012
Enrollment StartJun 1, 2012
Primary CompletionJan 1, 2013
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 14.2 years ago

Interventions

Lactobacillus reuteridietary

Will receive triple therapy (omeprazole 20 mg b.i.d., amoxicillin 1000 mg b.i.d, clarithromycin 500mg b.i.d) and L. reuteri (is a mixture of L. reuteri DSM 17938 and L. reuteri ATCC PTA 6475, will be delivered a dose of 1x108 CFU each strain, means giving daily chewable tablet containing 2x108 CFU/day) for 2 weeks followed by L. reuteri for another 2 weeks.

Placebodietary

Will receive triple therapy (omeprazole 20 mg b.i.d., amoxicillin 1000 mg b.i.d, clarithromycin 500mg b.i.d) and a placebo (1.5 mg per dose as chewable tablets) for 2 weeks followed by placebo for another 2 weeks.

Omeprazoledrug

All patients will receive omeprazole 20 mg b.i.d for 2 week

Amoxicillindrug

amoxicillin 1000 mg b.i.d for 2 weeks

Clarithromycindrug

clarithromycin 500mg b.i.d for 2 weeks