CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 19 enrolled
Drug / intervention
cabozantinib +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01599793
NCT01599793Phase 2Completed

A Phase II Study of MRI Based Functional Imaging for the Evaluation of Bone Metastasis in Men With Castrate Resistant Prostate Cancer Receiving XL184

University of Chicago·interventional·Posted May 16, 2012·Updated Mar 26, 2020

In Brief

A Phase 2 clinical trial evaluating cabozantinib, laboratory biomarker analysis, and 1 other intervention for Bone Metastases and 3 related conditions. Completed, enrolled 19 participants across 1 site.

Detailed Summary

This study is being done to help researchers understand more about prostate cancer that has spread to the bones by using the newest magnetic resonance imaging (MRI) techniques and to better understand the effect of an experimental drug called XL184 (or cabozantinib) on bone disease. The other purposes of the study are to better understand the effect of XL184 on prostate cancer progression, bone pain, and on any cancer cells that patients may have circulating within the blood (called circulating tumor cells)

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
CollaboratorsEndeavor Health

Timeline

Phase 2CompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedMay 16, 2012
Enrollment StartMay 1, 2012
Primary CompletionDec 1, 2017
Study CompletionDec 1, 2018
TodayJul 2, 2026
Enrollment to primary: 5.6 yearsPosted 14.1 years ago

Interventions

cabozantinibdrug

Given PO

laboratory biomarker analysisother

Correlative studies

magnetic resonance imagingprocedure

Undergo MRI