At a glance
ClinicalIndex Comparison RecordN/ACompleted· 53 enrolled
Drug / intervention
Estradioldrug
Likely dose
Estradiol 0.15mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Time Past Menopause, Duration of Estrogen Deficiency, and Insulin Action
In Brief
A clinical study evaluating Estradiol for Insulin Resistance. Completed, enrolled 53 participants across 1 site.
Detailed Summary
The aim of the current study is to test whether the effect of estrogen on insulin metabolism depends on the timing of treatment relative to when a woman went through menopause. The investigators hypothesize that estrogen will improve insulin sensitivity in early postmenopausal women, but decrease insulin sensitivity in late postmenopausal women.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsInsulin Resistance
CountriesUnited States
Timeline
N/ACompletedFinished
201220132014201520162017201820192020202120222023202420252026
Enrollment StartSep 2011
First PostedMay 2012
Primary CompletionNov 2015
Study CompletionJan 2017
TodayJul 2026
First PostedMay 24, 2012
Enrollment StartSep 1, 2011
Primary CompletionNov 1, 2015
Study CompletionJan 1, 2017
TodayJul 2, 2026
Enrollment to primary: 4.2 yearsPosted 14.1 years ago
Interventions
Estradioldrug
1 week of transdermal estradiol (0.15mg) 1 week of transdermal placebo