CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 10 enrolled
Drug / intervention
methotrexate +6 moredrug
Likely dose
methotrexate 7.5mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01619176
NCT01619176N/ACompleted
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Non Inferiority Trial for the Study of Acupuncture on Rheumatoid Arthritis

Chinese Academy of Sciences·interventional·Posted Jun 14, 2012·Updated Nov 13, 2023

In Brief

A clinical study evaluating methotrexate, non-steroidal anti-inflammatory drug (NSAID), and 2 other interventions for Rheumatoid Arthritis. Completed, enrolled 10 participants across 1 site.

Detailed Summary

Acupuncture is used and recommended by the WHO for the treatment of Rheumatoid Arthritis. The molecular bases of this recommendation are not known, the investigators want to compare with the usage of high-throughput molecular technologies the variations occurring in patients treated with acupuncture and conventional treatment with the ones treated with conventional treatment only. The investigators observe the variations in blood and in the gut microbiome.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsRheumatoid Arthritis
CountriesChina
CollaboratorsShanghai Guanghua Hospital of Integrated Traditional Chinese and Western Medicine

Timeline

N/ACompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedJun 14, 2012
Enrollment StartOct 1, 2012
Primary CompletionDec 1, 2014
TodayJul 2, 2026
Enrollment to primary: 2.2 yearsPosted 14.0 years ago

Interventions

methotrexatedrug

methotrexate: 7.5mg/week to 15mg/week for 3 months

non-steroidal anti-inflammatory drug (NSAID)drug

NSAID: 100mg twice a day for 3 months

leflunomidedrug

leflunomide: 20mg/day for 3 months

methotrexatedrug

methotrexate: 7.5mg/week to 15mg/week for 3 months

non-steroidal anti-inflammatory drug (NSAID)drug

NSAID: 100mg twice a day for 3 months

leflunomidedrug

leflunomide: 20mg/day for 3 months

Acupunctureprocedure

30 minutes acupuncture every other day for 3 months. Basic acupoints: Zusanli, st36; Taixi，KI3）; Shenxu, BL23 Additional acupoints due to personal condition: Waiguan，SJ5; Baxie，Ex-UE9;Yinlingquan，(SP9）; Quchi，LI11; Yanglingquan，GB34; Xuehai，SP10; Dazhu，BL11; Dazhui，DU14; Pixu，BL20.