At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A PROSPECTIVE EVALUATION OF THE RADIOGRAPHIC EFFICACY OF ETANERCEPT IN PATIENTS WITH RHEUMATOID ARTHRITIS OR PSORIATIC ARTHRITIS.
In Brief
An observational study evaluating Etanercept for Rheumatoid Arthritis and Psoriasis Arthritis. Completed, enrolled 1,821 participants.
Detailed Summary
It is known from the COMET-trial that patients who start Enbrel treatment early have a great chance of reaching clinical remission and radiographic nonprogression. It is still unclear, however, how many patients with early arthritis achieve remission and radiographic nonprogression under the conditions of routine rheumatologic care and the local recommendations of Enbrel treatment (pre-treatment of at least 2 DMARDs, one of them MTX). Therefore, no robust x-ray data are available to show/demonstrate * the average extent of x-ray damage in routine patients on Enbrel outside clinical studies. * if the outstanding effect on structural damage of Enbrel can be reproduced in routine practice. * that the 'Silent Progressor' is an issue relevant not only in clinical trials, but also for day-to-day decision making. * the optimal onset of Enbrel treatment in the course of the disease to prevent radiographic damage
Study Details
Timeline
Interventions
The patients will be treated in accordance with the requirements of the labelling of Enbrel® in Germany. The dosage and duration of therapy is to be determined by the physician to meet the patients' individual needs for treatment.
The patients will be treated in accordance with the requirements of the labelling of Enbrel® in Germany. The dosage and duration of therapy is to be determined by the physician to meet the patients' individual needs for treatment.