CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 82 enrolled
Drug / intervention
Topiramate +1 moredrug
Likely dose
Topiramate 200 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01641445
NCT01641445Phase 2Completed
CompareCT.gov

Effects of Topiramate on Adolescent Alcohol Use: Efficacy and Mechanisms

Brown University·interventional·Posted Jul 16, 2012·Updated Oct 20, 2020

In Brief

A Phase 2 clinical trial evaluating Topiramate and Placebo for Alcohol Drinking. Completed, enrolled 82 participants across 1 site.

Detailed Summary

This study will help to determine whether the medication, topiramate, reduces alcohol use among adolescents with alcohol dependence. It will also help answer the question, "How does topiramate reduce drinking in teenagers?" Understanding how topiramate may reduce drinking in adolescents would allow for a more targeted pharmacotherapeutic approach to treatment and help to identify additional medications that may hold promise for improving treatment outcomes for youth.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAlcohol Drinking
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedJul 16, 2012
Enrollment StartJul 1, 2012
Primary CompletionMay 1, 2016
Study CompletionApr 12, 2017
TodayJul 2, 2026
Enrollment to primary: 3.8 yearsPosted 14.0 years ago

Interventions

Topiramatedrug

Topiramate (200 mg daily)

Placebodrug

Matching placebo capusules ("sugar pills"