At a glance
ClinicalIndex Comparison RecordPhase 4Completed· 60 enrolled
Drug / intervention
locally-applied minocycline HCl (1 mg) +1 moredrug
Likely dose
locally-applied minocycline HCl (1 mg)from record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Local Minocycline to Reduce Future Inflammation and Bone Loss in Periodontal Maintenance Patients
In Brief
A Phase 4 clinical trial evaluating locally-applied minocycline HCl (1 mg) and scaling and root planing (Sc/RP) for Moderate to Advanced Chronic Periodontitis. Completed, enrolled 60 participants across 2 sites.
Detailed Summary
The purpose of this study is to determine the effect of local application of minocycline microspheres on the periodontal inflammation and bone loss prevention in patients diagnosed with moderate-severe chronic periodontitis within a periodontal maintenance program.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--
Timeline
Phase 4CompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedJul 2012
Enrollment StartOct 2012
Primary CompletionDec 2015
TodayJul 2026
First PostedJul 23, 2012
Enrollment StartOct 1, 2012
Primary CompletionDec 1, 2015
TodayJul 2, 2026
Enrollment to primary: 3.2 yearsPosted 13.9 years ago
Interventions
locally-applied minocycline HCl (1 mg)drug
scaling and root planing (Sc/RP)procedure