CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 93 enrolled
Drug / intervention
Belimumab 10 mg/kg +1 moredrug
Likely dose
Belimumab 10 mg/kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01649765
NCT01649765Phase 2Completed

A Multi-center, Randomized, Placebo-Controlled Trial to Evaluate the Safety, Efficacy, and Pharmacokinetics of Belimumab, a Human Monoclonal Anti-BLyS Antibody, Plus Standard Therapy in Pediatric Patients With Systemic Lupus Erythematosus

GlaxoSmithKline·interventional·Posted Jul 25, 2012·Updated Apr 20, 2026

In Brief

A Phase 2 clinical trial evaluating Belimumab 10 mg/kg and Placebo for Systemic Lupus Erythematosus. Completed, enrolled 93 participants across 32 sites in 10 countries.

Detailed Summary

This is a multi-center study to evaluate the safety, pharmacokinetics, and efficacy of belimumab intravenous (IV) in pediatric patients 5 to 17 years of age with active systemic lupus erythematosus

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesArgentina, Canada, Japan, Mexico, Peru, Poland, Russia, Spain, United Kingdom, United States

Timeline

Phase 2CompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedJul 25, 2012
Enrollment StartSep 7, 2012
Primary CompletionJan 24, 2018
Study CompletionSep 30, 2025
TodayJul 2, 2026
Enrollment to primary: 5.4 yearsPosted 13.9 years ago

Interventions

Belimumab 10 mg/kgdrug

Belimumab was administered.

Placeboother

Placebo was administered