At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Effects of Evoked Resistance Training and Testosterone After Spinal Cord Injury
In Brief
A Phase 3 clinical trial evaluating Resistance Training and Testosterone Patches and Testosterone Patches for Spinal Cord Injury. Completed, enrolled 26 participants across 1 site.
Detailed Summary
The goal of this proposal is to investigate the efficacy of a complimentary approach of evoked resistance training and testosterone replacement therapy on the changes in body composition and metabolic profile after SCI. The proposed method could become a recommended and simple intervention especially for individuals with limited access and poor tolerance to exercise. The rationale is based on the evidence that individuals with SCI experience decline in anabolic hormones which may be responsible for the deterioration in body composition and metabolic profiles and leads to increase obesity, type 2 diabetes mellitus, dyslipidemia and subsequently cardiovascular disease. The designed study will provide explanation to the adaptations in the energy source of the muscle cells in response to training.
Study Details
Timeline
Interventions
We are going to activate the knee extensor muscle group to lift ankle weights over 16 weeks and we are going to provide Tp to improve anabolic profile.
The investigators will provide Tp patches for 16 weeks for patients with Spinal Cord Injury.