CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 40 enrolled
Drug / intervention
Synera +1 moredrug
Likely dose
Synera 70 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01654302
NCT01654302Phase 2Completed
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Efficacy and Safety of Synera in OA Pain

Thomas J. Schnitzer·interventional·Posted Jul 31, 2012·Updated May 12, 2015

In Brief

A Phase 2 clinical trial evaluating Synera and Inactive patch for Knee Osteoarthritis. Completed, enrolled 40 participants across 1 site.

Detailed Summary

Knee osteoarthritis (OA) can result in significant pain and limitation of function. A number of topical non-steroidal anti-inflammatory drugs have been shown to reduce pain in this condition. This study examines a different topical approach, utilizing a topical anesthetic agent, to evaluate if application of such an agent would provide relief of exercise-induced knee pain in people with knee OA.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsKnee Osteoarthritis
CountriesUnited States
CollaboratorsNuvo Research Inc.

Timeline

Phase 2CompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedJul 31, 2012
Enrollment StartSep 1, 2013
Primary CompletionSep 1, 2014
Study CompletionFeb 1, 2015
TodayJul 2, 2026
Enrollment to primary: 1 yearPosted 13.9 years ago

Interventions

Syneradrug

70 mg lidocaine/ 70 mg tetracaine topical patch applied once for 12 hours

Inactive patchdrug

placebo patch applied once for 12 hours