CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 100 enrolled
Drug / intervention
Calcium sodium phosphosilicate +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01657877
NCT01657877Phase 2Completed
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In Situ Study to Confirm the Anti-caries Potential of a 1.1365% w/w Sodium Monofluorophosphate (1500ppm F) Dentifrice

GlaxoSmithKline·interventional·Posted Aug 6, 2012·Updated Oct 1, 2014

In Brief

A Phase 2 clinical trial evaluating Calcium sodium phosphosilicate, Sodium monoflurophosphate, and 1 other intervention for Caries. Completed, enrolled 100 participants across 1 site.

Detailed Summary

In situ study to compare treatment effect on enamel remineralization potential, measured by surface microhardness recovery (SMHR) and Enamel Fluoride Uptake (EFU). The study will explore the efficacy of an experimental sodium monofluorophosphate (SMFP) dentifrice containing calcium sodium phosphosilicate (CSP) in comparison to an experimental SMFP only dentifrice.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCaries
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedAug 6, 2012
Enrollment StartMay 1, 2012
Primary CompletionJun 1, 2013
TodayJul 2, 2026
Enrollment to primary: 1.1 yearsPosted 13.9 years ago

Interventions

Calcium sodium phosphosilicatedrug

CSP high percentage weight by weight

Sodium monoflurophosphatedrug

500 to 1500 parts per million (ppm) of fluoride

Placebodrug

No CSP and no fluoride