CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 17 enrolled
Drug / intervention
Hydrochlorothiazide +4 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01658657
NCT01658657N/ACompleted
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A Pilot Study of Plasma Renin Activity Guided vs Generic Combination Therapy for Hypertension

University of North Carolina, Chapel Hill·interventional·Posted Aug 7, 2012·Updated Aug 27, 2015

In Brief

A clinical study evaluating Hydrochlorothiazide, Lisinopril, and 3 other interventions for Hypertension and Plasma Renin Activity. Completed, enrolled 17 participants across 1 site.

Detailed Summary

The purpose of this study is to investigate the effect of plasma renin activity-guided therapy for determining hypertension treatment. Plasma renin is an enzyme in your blood that can be measured to determine your hypertension subtype. Once the subtype is known, doctors can prescribe specific medications to target your specific hypertension subtype. This study will investigate whether targeting the specific hypertension subtype helps to achieve blood pressure control sooner and with fewer medications compared to a standard fixed dose combination therapy.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHypertension, Plasma Renin Activity
CountriesUnited States
CollaboratorsCornell University, Wake Forest University Health Sciences

Timeline

N/ACompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedAug 7, 2012
Enrollment StartOct 1, 2012
Primary CompletionJul 1, 2014
TodayJul 2, 2026
Enrollment to primary: 1.8 yearsPosted 13.9 years ago

Interventions

Hydrochlorothiazidedrug

Lisinoprildrug

Amlodipinedrug

metoprololdrug

lisinopril/hydrochlorothiazidedrug

This is a combination pill