CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 16 enrolled
Drug / intervention
Minocyclinedrug
Likely dose
Minocycline 100 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01659320
NCT01659320N/ACompleted
CompareCT.gov

Open Treatment of Minocycline in Geriatric Depression

Weill Medical College of Cornell University·interventional·Posted Aug 7, 2012·Updated May 12, 2017

In Brief

A clinical study evaluating Minocycline for Depression. Completed, enrolled 16 participants across 1 site.

Detailed Summary

This research study will examine whether elderly depressed patients whose depressive symptoms do not respond satisfactorily to therapy with a mood stabilizer or antidepressant alone gain any benefit from taking minocycline alone or in addition to their antidepressant or mood stabilizer medication. Minocycline is a commonly used antibiotic medication with anti-inflammatory properties. It is hoped that information gained from this study will help the investigators better understand the role of inflammation in depression, and whether decreasing inflammation will lead to improvement in the symptoms of depression and cognitive function.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDepression
CountriesUnited States
CollaboratorsNational Institute of Mental Health (NIMH)

Timeline

N/ACompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedAug 7, 2012
Enrollment StartMar 1, 2012
Primary CompletionApr 1, 2015
TodayJul 2, 2026
Enrollment to primary: 3.1 yearsPosted 13.9 years ago

Interventions

Minocyclinedrug

Minocycline 100 mg twice daily for 8 weeks