CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 1,202 enrolled
Drug / intervention
3T CMR +4 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01664858
NCT01664858N/ACompleted
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Clinical Evaluation of Magnetic Resonance Imaging in Coronary Heart Disease - 2 (CE-MARC2)

University of Leeds·interventional·Posted Aug 14, 2012·Updated Nov 23, 2018

In Brief

A clinical study evaluating 3T CMR, SPECT, and 3 other interventions for Coronary Heart Disease. Completed, enrolled 1,202 participants across 6 sites.

Detailed Summary

CE-MARC 2 is a randomised controlled trial to determine diagnosis and patient management in patients presenting to outpatient clinics with suspected stable angina. Cardiac Magnetic Resonance Imaging (at 3Tesla) will be evaluated prospectively against current best clinical practice (defined by international guidelines). The study hypothesis is that 3Tesla CMR-guided management of patients with suspected stable angina is superior to current clinical practice based on 1) the principles of the National Institutes for Clinical Excellence (NICE) CG95 guidelines (2010); 2) SPECT AHA appropriateness criteria, in terms of avoiding study-defined unnecessary invasive coronary angiography.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCoronary Heart Disease
CountriesUnited Kingdom
CollaboratorsUniversity of Leicester, University of Glasgow, British Heart Foundation

Timeline

N/ACompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedAug 14, 2012
Enrollment StartNov 1, 2012
Primary CompletionMar 1, 2016
Study CompletionMar 1, 2018
TodayJul 2, 2026
Enrollment to primary: 3.3 yearsPosted 13.9 years ago

Interventions

3T CMRother

3Tesla Cardiac Magnetic Resonance Imaging

SPECTother

SPECT: Single Photon Emission Computed Tomography

CT calcium scoreother

CT calcium score

CT coronary angiographyother

CT coronary angiography

X-Ray coronary angiographyother

X-Ray coronary angiography