At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Improving Diabetes Through Lifestyle and Surgery Study
In Brief
A Phase 3 clinical trial evaluating Gastric Banding, Medical Weight Loss, and 1 other intervention for Obesity and Type 2 Diabetes. Completed, enrolled 15 participants across 1 site.
Detailed Summary
Weight loss is effective in reducing many complications of obesity, with the majority of patients who undergo bariatric surgery having substantial improvements in their weight-related illnesses. The investigators propose a pilot study in 45 subjects with mild to moderate obesity to compare how losing 10% of initial body weight via one of three common weight loss strategies (medical weight loss with a low calorie diet, Roux-en-Y gastric bypass surgery, and adjustable gastric banding) affects diabetes. While the investigators do not expect this pilot study to provide definitive answers, it will provide valuable information to design a larger trial which will help guide therapy for people with mild-moderate obesity and substantial comorbidities.
Study Details
Timeline
Interventions
Laparoscopic Adjustable Gastric Banding using the LapBand
Weight loss intervention using diet (meal replacments), physical activity and behavioral techniques administered with weekly one-on-one counselling by dieticians
Laparoscopic Roux-en-Y Gastric Bypass