CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 81 enrolled
Drug / intervention
Corticosteroid injection +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01670825
NCT01670825N/ACompleted

Randomized, Double-blind, Comparative-effectiveness Study Comparing Corticosteroid Injections to Pulsed Radiofrequency for Occipital Neuralgia

Johns Hopkins University·interventional·Posted Aug 22, 2012·Updated Mar 1, 2017

In Brief

A clinical study evaluating Pulsed radiofrequency, Corticosteroid injection, and 1 other intervention for Occipital Neuralgia. Completed, enrolled 81 participants across 2 sites.

Detailed Summary

The aim of this study is to determine whether pulsed radiofrequency or steroids are better for occipital neuralgia. Seventy-six patients with ON or migraine with tenderness over the occipital nerve who respond to occipital nerve blocks (hereafter included under the broad category "ON") will be randomized in a 1:1 ratio to receive either corticosteroid and local anesthetic injections (n=38) or local anesthetic and PRF of the occipital nerve(s) (n=38) for occipital neuralgia. Both patients and the treating \& evaluating physicians will be blinded. The first follow-up visit will be at 6 weeks. Patients who obtain significant pain relief will remain in the study. Those patients who fail to obtain any benefit will exit the study and be allowed to crossover to the other treatments or receive alternative care. The second follow-up will be at 3 months and the final follow-up will be at 6-months post-procedure.

Study Details

Timeline

N/ACompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedAug 22, 2012
Enrollment StartAug 1, 2012
Primary CompletionFeb 1, 2015
TodayJul 2, 2026
Enrollment to primary: 2.5 yearsPosted 13.9 years ago

Interventions

Pulsed radiofrequencyprocedure

Local anesthetic injection and pulsed radiofrequency treatment x 6 minutes over each affected occipital nerve

Corticosteroid injectiondrug

Corticosteroid and local anesthetic injection plus sham pulsed radiofrequency over each affected occipital nerve

Local anethestic injectiondrug