CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 55 enrolled
Drug / intervention
Anodal tDCS +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01673126
NCT01673126Phase 2Completed
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Transcranial Direct Current Stimulation in Patients With Disorders of Consciousness: a Sham-controlled Randomised Double Blind Study

University of Liege·interventional·Posted Aug 27, 2012·Updated Jun 9, 2014

In Brief

A Phase 2 clinical trial evaluating Anodal tDCS and sham tDCS for Vegetative State and 2 related conditions. Completed, enrolled 55 participants across 1 site.

Detailed Summary

Previous studies showed that anodal transcranial direct current stimulation (tDCS) applied to the left dorsolateral prefrontal (DLPF) cortex transiently improves performance of memory and attention. Investigator assessed the effects of left DLPF-tDCS on Coma Recovery Scale-Revised (CRS-R) scores in severely brain damaged patients with disorders of consciousness in a double-blind sham-controlled experimental design.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsVegetative State, Minimally Conscious State, Disorders of Consciousness
CountriesBelgium
Collaborators--

Timeline

Phase 2CompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
First PostedAug 27, 2012
Enrollment StartJan 1, 2010
Primary CompletionAug 1, 2010
Study CompletionDec 1, 2011
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 13.8 years ago

Interventions

Anodal tDCSdevice

patients received anodal tDCS (on PFDL cortex) during 20 minutes preceded and followed by a behavioral assessment (Coma Recovery Scale Revised)

sham tDCSdevice

Patient received a sham tDCS (5sec of stimulation). The device runs during 20minutes and the anode was placed over the DLPF cortex. A behavioral assessment preceded and followed the stimulation.