CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 13 enrolled
Drug / intervention
Allopregnanolone injection +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01673828
NCT01673828Phase 2Completed

A Double-blind, Placebo-controlled, Randomized Clinical Trial of Allopregnanolone for the Treatment of Traumatic Brain Injury

Michael A. Rogawski, MD, PhD·interventional·Posted Aug 28, 2012·Updated Jun 28, 2017

In Brief

A Phase 2 clinical trial evaluating Allopregnanolone injection and Placebo injection for Traumatic Brain Injury and Posttraumatic Epilepsy. Completed, enrolled 13 participants across 1 site.

Detailed Summary

This study will provide initial data on the safety and effectiveness of allopregnanolone in improving neurobehavioral outcome and reducing mortality in adults with moderate and severe traumatic brain injury.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 2CompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedAug 28, 2012
Enrollment StartApr 1, 2013
Primary CompletionMay 1, 2015
Study CompletionJul 1, 2016
TodayJul 2, 2026
Enrollment to primary: 2.1 yearsPosted 13.8 years ago

Interventions

Allopregnanolone injectiondrug

Allopregnanolone intravenous solution in 0.9% sodium chloride injection with 6% sulfobutyl ether β-cyclodextrin sodium

Placebo injectiondrug

Placebo intravenous solution, 0.9% sodium chloride injection with 6% sulfobutyl ether β-cyclodextrin sodium