At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Increased Plasma Nitrite, Tissue Oxygenation and Functional Changes in PAD
In Brief
A Phase 2 clinical trial evaluating Beetroot Juice (Beet-It Stamina Shot) & Supervised Exercise Training and Placebo Comparator Beverage (Beet-It Stamina Shot) & Exercise Training for Peripheral Arterial Disease. Completed, enrolled 32 participants across 1 site.
Detailed Summary
The hypothesis of this proposal is that in subjects with PAD, regular consumption of a high nitrate supplement which raises plasma nitrite, in conjunction with 12 weeks of supervised exercise training at the limb ischemic threshold (SET) will produce a greater clinical benefit (increases in COT and PWT) than placebo plus supervised exercise at the limb ischemic threshold (PET).
Study Details
Timeline
Interventions
The beverage is high in inorganic nitrate and bottled and supplied by James White Drinks. This supplement will be used in conjunction with supervised exercise training.
The beverage is identical in look and taste to Beet-It Stamina Shot but with active ingredient removed. It is also bottled and supplied by James White Drinks. This placebo supplement will be used in conjunction with supervised exercise training.