At a glance
ClinicalIndex Comparison RecordN/ACompleted· 33 enrolled
Drug / intervention
Multiplex pharmacokinetic profiling +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Selecting Insulin Analogs for Closed-Loop Control Using Multiplex Pharmacokinetic Profiling
In Brief
A clinical study evaluating Multiplex pharmacokinetic profiling and Continuous insulin monitoring for Type 1 Diabetes. Completed, enrolled 33 participants across 1 site.
Detailed Summary
The investigators are doing this research study to compare the pharmacokinetics (PK) (rate of absorption) of insulin lispro (Humalog), insulin aspart (Novolog), and insulin glulisine (Apidra) within individual subjects. Additionally, the investigators will perform a preliminary feasibility evaluation of a minimally invasive continuous insulin monitoring (CIM) device and its use to derive PK parameters in human subjects.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsType 1 Diabetes
CountriesUnited States
Collaborators--
Timeline
N/ACompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
Enrollment StartJul 2010
First PostedSep 2012
Primary CompletionSep 2016
Study CompletionDec 2017
TodayJul 2026
First PostedSep 13, 2012
Enrollment StartJul 1, 2010
Primary CompletionSep 1, 2016
Study CompletionDec 1, 2017
TodayJul 2, 2026
Enrollment to primary: 6.2 yearsPosted 13.8 years ago
Interventions
Multiplex pharmacokinetic profilingother
Continuous insulin monitoringother