At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Effect of Acetyl-L-carnitine in Migraine - a Randomized, Double-blind Placebo Controlled Study
In Brief
A Phase 4 clinical trial evaluating Acetyl-L-carnitine for Migraine. Completed, enrolled 72 participants across 1 site.
Detailed Summary
Traditionally, beta blockers have been used for migraine prophylaxis, but in later years also antiepileptic drugs. Contraindications and side effects have to some degree limited their use, and new prophylactics that can be used by most migraine sufferers and with little side effects are in demand. One product that may seem to fulfill these requirements is Acetyl-L-carnitine, which is a dietary supplement and naturally occurs in plants and animals. L-carnitine is necessary for fatty-acid metabolism and energy production. To our knowledge, no placebo-controlled studies have previously evaluated the efficacy of Acetyl-L-carnitine in adults with migraine. The aims of the present study is to evaluate the efficacy of Acetyl-L-carnitine as a prophylaxis in migraine patients
Study Details
Timeline
Interventions
Week 1: 500 mg x 3, Week 2-12: 500 mg x 6