CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 20 enrolled
Drug / intervention
Desflurane +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01700907
NCT01700907Phase 2Completed

Optimization of Desflurane in Elderly Patients Compared With Sevoflurane: A Pilot Study

Sapporo Medical University·interventional·Posted Oct 4, 2012·Updated Nov 27, 2014

In Brief

A Phase 2 clinical trial evaluating Desflurane and Sevoflurane for Postoperative Cognitive Dysfunction. Completed, enrolled 20 participants across 1 site.

Detailed Summary

Various issues had been pointed out when undergoing the anesthesia for elderly patients with sevoflurane, such as delayed emergence, post-operative trouble with swallowing. Desflurane, which has a lower blood/gas partition coefficient, is expected to contribute the better emergence, along with the recent progress on optimization of delivered amount of anesthesia. The purpose of this study is to compare the time to emergence in long elderly patient cases with desflurane or sevoflurane, with the recently developed drug-delivery optimization system "Aisys®" (GE Healthcare Japan).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesJapan
Collaborators--

Timeline

Phase 2CompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedOct 4, 2012
Enrollment StartAug 1, 2012
Primary CompletionFeb 1, 2013
TodayJul 2, 2026
Enrollment to primary: 6 monthsPosted 13.7 years ago

Interventions

Desfluranedrug

The patients in this arm will be given the general anesthesia with desflurane and be used the Aysis as the anesthetic machine.

Sevofluranedrug

The patients in this arm will be given the general anesthesia with sevoflurane and be used the Aysis as the anesthetic machine.