CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 100 enrolled
Drug / intervention
Vapocoolant (Pain Ease) +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01712776
NCT01712776N/ACompleted

Prospective, Randomized, Blinded,Comparative Efficacy and Safety Trial of Vapocoolant (Pain Ease Medium Stream) for Venipuncture

The Cleveland Clinic·interventional·Posted Oct 24, 2012·Updated Aug 29, 2025

In Brief

A clinical study evaluating Vapocoolant (Pain Ease) and Nature's Tears Sterile Water for Pain. Completed, enrolled 100 participants across 1 site.

Detailed Summary

To determine the efficacy and safety of vapocoolant spray (Pain Ease Medium Stream) in decreasing the pain of venipuncture ("blood draw")

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPain
CountriesUnited States
CollaboratorsGebauer Company

Timeline

N/ACompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedOct 24, 2012
Enrollment StartApr 1, 2011
Primary CompletionFeb 1, 2012
TodayJul 2, 2026
Enrollment to primary: 10 monthsPosted 13.7 years ago

Interventions

Vapocoolant (Pain Ease)device

Topical stream 4-10 seconds duration to skin.

Nature's Tears Sterile Waterdevice

Topical stream 4-10 seconds duration to skin