CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 772 enrolled
Drug / intervention
Tildrakizumab 200 mg +2 moredrug
Likely dose
Tildrakizumab 200 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01722331
NCT01722331Phase 3Completed

A 64-Week, Phase 3, Randomized, Placebo-Controlled, Parallel Design Study to Evaluate the Efficacy and Safety/Tolerability of Subcutaneous Tildrakizumab (SCH 900222/MK-3222), Followed by an Optional Long-Term Safety Extension Study, in Subjects With Moderate-to-Severe Chronic Plaque Psoriasis (Protocol No. MK-3222-010)

Sun Pharmaceutical Industries Limited·interventional·Posted Nov 6, 2012·Updated Mar 23, 2022

In Brief

A Phase 3 clinical trial evaluating Tildrakizumab 200 mg, Tildrakizumab 100 mg, and 1 other intervention for Plaque Psoriasis. Completed, enrolled 772 participants.

Detailed Summary

This study is being conducted to evaluate the efficacy and safety/tolerability of subcutaneous tildrakizumab (MK-3222), followed by an optional long-term safety extension study, in participants with moderate-to-severe chronic plaque psoriasis.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
Countries--
Collaborators--

Timeline

Phase 3CompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedNov 6, 2012
Enrollment StartDec 6, 2012
Primary CompletionOct 28, 2015
Study CompletionNov 10, 2021
TodayJul 2, 2026
Enrollment to primary: 2.9 yearsPosted 13.7 years ago

Interventions

Tildrakizumab 200 mgdrug

Two tildrakizumab 100 mg/mL pre-filled syringes (PFS)

Tildrakizumab 100 mgdrug

Tildrakizumab 100 mg/mL PFS

Matching Placebodrug

Matching placebo to tildrakizumab PFS