CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 85 enrolled
Drug / intervention
Clinical Observation +5 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01725165
NCT01725165Phase 2Completed

A Randomized Phase II Study Assessing the Efficacy of Local Consolidative Therapy for Non-Small Cell Lung Cancer Patients With Induced Oligometastatic Disease

M.D. Anderson Cancer Center·interventional·Posted Nov 12, 2012·Updated Oct 24, 2024

In Brief

A Phase 2 clinical trial evaluating Clinical Observation, External Beam Radiation Therapy, and 4 other interventions for Recurrent Lung Non-Small Cell Carcinoma and Stage IV Non-Small Cell Lung Cancer AJCC v7. Completed, enrolled 85 participants across 3 sites in 2 countries.

Detailed Summary

This randomized phase II trial studies how well surgery and/or radiation therapy or standard therapy and/or clinical observation works in treating patients with previously treated stage IV non-small cell lung cancer. Radiation therapy uses high energy x-rays to kill tumor cells. Giving surgery and/or radiation therapy may be more effective than standard therapy and/or clinical observation in patients with previously treated non-small cell lung cancer.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesCanada, United States

Timeline

Phase 2CompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedNov 12, 2012
Enrollment StartNov 28, 2012
Primary CompletionMay 8, 2024
TodayJul 2, 2026
Enrollment to primary: 11.4 yearsPosted 13.6 years ago

Interventions

Clinical Observationother

Undergo clinical observation

External Beam Radiation Therapyradiation

Undergo EBRT

Laboratory Biomarker Analysisother

Optional correlative studies

Quality-of-Life Assessmentother

Ancillary studies

Standard Follow-Up Careprocedure

Undergo standard maintenance therapy

Therapeutic Conventional Surgeryprocedure

Undergo surgery