CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 496 enrolled
Drug / intervention
BI 207127-placebo: 8-week treatment +11 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01728324
NCT01728324Phase 3Completed

A Phase III Randomised, Partially Double-blind and Placebo-controlled Study of BI 207127 in Combination With Faldaprevir and Ribavirin for Chronic Genotype 1 Hepatitis C Infection in an Extended Population of Treatment naïve Patients That Includes Those Ineligible to Receive Peginterferon

Boehringer Ingelheim·interventional·Posted Nov 19, 2012·Updated Feb 12, 2016

In Brief

A Phase 3 clinical trial evaluating BI 207127-placebo: 8-week treatment, Ribavirin: 24-week treatment, and 8 other interventions for Hepatitis C, Chronic. Completed, enrolled 496 participants across 109 sites in 12 countries.

Detailed Summary

The aim of the study is to confirm efficacy and safety of treatment with 600 mg of BID BI 207127 in combination with 120 mg QD FDV and RBV for 16 or 24 weeks in target chronically infected HCV GT1b treatment naïve patients, including patients with compensated cirrhosis.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustralia, Belgium, Canada, France, Germany, Greece, Italy, New Zealand, Portugal, Spain, United Kingdom, United States
Collaborators--

Timeline

Phase 3CompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedNov 19, 2012
Enrollment StartNov 1, 2012
Primary CompletionFeb 1, 2014
Study CompletionJan 1, 2015
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 13.6 years ago

Interventions

BI 207127-placebo: 8-week treatmentdrug

8 weeks of placebo treatment

Ribavirin: 24-week treatmentdrug

24 weeks of active treatment

BI 207127: 24-week treatmentdrug

24 weeks of active treatment

Faldaprevir: 24-week treatmentdrug

24 weeks of active treatment

Faldaprevir: 24-week treatmentdrug

24 weeks of active treatment

Ribavirin-placebo: 8-week treatmentdrug

8 weeks of placebo treatment

BI 207127: 24-week treatmentdrug

24 weeks of active treatment

Faldaprevir-placebo: 8-week treatmentdrug

8 weeks of placebo treatment

Faldaprevir: 16-week treatmentdrug

16 weeks of active treatment

Ribavirin: 16-week treatmentdrug

16 weeks of active treatment

RBV: 24-week treatmentdrug

24 weeks of active treatment

BI 207127: 16-week treatmentdrug

16 weeks of active treatment