At a glance
ClinicalIndex Comparison RecordPhase 1Completed· 48 enrolled
Drug / intervention
dabigatran etexilate +5 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Investigation of Drug-drug Interaction of Dabigatran and Ticagrelor Under Steady State Conditions in Healthy Male Subjects
In Brief
A Phase 1 clinical trial evaluating dabigatran etexilate and ticagrelor for Healthy. Completed, enrolled 48 participants across 1 site.
Detailed Summary
To investigate the pharmacokinetic and pharmacodynamic interaction of dabigatran and ticagrelor under steady state conditions; to investigate the effect of staggered administration of ticagrelor loading dose on dabigatran exposure (in Part II)
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHealthy
CountriesGermany
Collaborators--
Timeline
Phase 1CompletedFinished
20132014201520162017201820192020202120222023202420252026
Enrollment StartNov 2012
First PostedNov 2012
Primary CompletionJun 2013
TodayJul 2026
First PostedNov 28, 2012
Enrollment StartNov 1, 2012
Primary CompletionJun 1, 2013
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 13.6 years ago
Interventions
dabigatran etexilatedrug
multiple doses of dabigatran
dabigatran etexilatedrug
medium dose dabigatran
ticagrelordrug
loading dose of ticagrelor
ticagrelordrug
multiple doses of ticagrelor
ticagrelordrug
loading dose of ticagrelor
dabigatran etexilatedrug
single dose of dabigatran