CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 106 enrolled
Drug / intervention
3H+ (Holistic Health for HIV) +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01741311
NCT01741311N/ACompleted
CompareCT.gov

Secondary HIV Prevention and Adherence Among HIV-infected Drug Users

University of Connecticut·interventional·Posted Dec 4, 2012·Updated Aug 8, 2025

In Brief

A clinical study evaluating 3H+ (Holistic Health for HIV) and HHRP+ (Holistic Health Recovery Program) for Risk Behavior and 2 related conditions. Completed, enrolled 106 participants across 1 site.

Detailed Summary

This study will test whether 3H+ (Holistic Health for HIV) is comparable to the original HHRP+ (Holistic Health Recovery Program) in reducing HIV risk behaviors and improving ART (Antiretroviral Therapy) adherence in a randomized controlled comparative effectiveness trial among 256 HIV+ persons in drug treatment who report unsafe injection drug use practices or sexual risk behavior.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsRisk Behavior, Medication Adherence, HIV
CountriesUnited States
CollaboratorsNational Institute on Drug Abuse (NIDA), Yale University, APT Foundation, Inc.

Timeline

N/ACompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedDec 4, 2012
Enrollment StartSep 1, 2012
Primary CompletionJun 1, 2018
TodayJul 2, 2026
Enrollment to primary: 5.8 yearsPosted 13.6 years ago

Interventions

3H+ (Holistic Health for HIV)behavioral

Four weekly HIV-risk reduction groups and an additional booster group held at week twelve summarizing the previous sessions' content, designed for opioid-dependent individuals living with HIV.

HHRP+ (Holistic Health Recovery Program)behavioral

12 two-hour group sessions addressing HIV risk reduction behavior and recovery for opioid-dependent individuals living with HIV.