At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Pilot Trial of Tubes to Prevent Ventilator-Associated Pneumonia (PreVent)
In Brief
A clinical study evaluating PVC ETT, PUC ETT, and 1 other intervention for Ventilator-acquired Pneumonia. Completed, enrolled 117 participants across 1 site.
Detailed Summary
Researchers are looking at three different types of breathing tubes to see if any of them are better at preventing pneumonia than the others. Two of the tubes have design features to prevent leakage of fluids from the mouth and throat into the lungs. This is importance, since leakage of small amounts of fluid into the lungs may lead to pneumonia. The third tube is the standard tube used at most hospitals. The hypothesis is that the use of a breathing tube that reduces fluid leakage into the lungs will reduce the risk of developing pneumonia, compared to the standard tube. The study will also look at the safety of the modified breathing tubes, compared to the standard tube. This study is a small, "pilot" study that will determine if it is possible to perform a larger study that will provide more certain results.
Study Details
Timeline
Interventions
Placement of a PVC-cuffed ETT in the setting of emergent intubation.
Placement of a PUC-cuffed ETT in the setting of emergent intubation.
Placement of a PUC-cuffed in the setting of emergent intubation, followed by continuous aspiration of subglottic secretions for the duration of mechanical ventilation.