CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 117 enrolled
Drug / intervention
PVC ETT +2 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01744483
NCT01744483N/ACompleted

Pilot Trial of Tubes to Prevent Ventilator-Associated Pneumonia (PreVent)

University of Washington·interventional·Posted Dec 6, 2012·Updated Oct 26, 2017

In Brief

A clinical study evaluating PVC ETT, PUC ETT, and 1 other intervention for Ventilator-acquired Pneumonia. Completed, enrolled 117 participants across 1 site.

Detailed Summary

Researchers are looking at three different types of breathing tubes to see if any of them are better at preventing pneumonia than the others. Two of the tubes have design features to prevent leakage of fluids from the mouth and throat into the lungs. This is importance, since leakage of small amounts of fluid into the lungs may lead to pneumonia. The third tube is the standard tube used at most hospitals. The hypothesis is that the use of a breathing tube that reduces fluid leakage into the lungs will reduce the risk of developing pneumonia, compared to the standard tube. The study will also look at the safety of the modified breathing tubes, compared to the standard tube. This study is a small, "pilot" study that will determine if it is possible to perform a larger study that will provide more certain results.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedDec 6, 2012
Enrollment StartDec 1, 2012
Primary CompletionOct 1, 2015
Study CompletionFeb 1, 2016
TodayJul 2, 2026
Enrollment to primary: 2.8 yearsPosted 13.6 years ago

Interventions

PVC ETTdevice

Placement of a PVC-cuffed ETT in the setting of emergent intubation.

PUC ETTdevice

Placement of a PUC-cuffed ETT in the setting of emergent intubation.

PUC-CASS ETTdevice

Placement of a PUC-cuffed in the setting of emergent intubation, followed by continuous aspiration of subglottic secretions for the duration of mechanical ventilation.