CI

At a glance

ClinicalIndex Comparison Record
Phase 2Unknown· 44 enrolled
Drug / intervention
Stereotactic Body Radiation Therapy (SBRT) +1 moreradiation
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01753414
NCT01753414Phase 2Unknown

POSTILV: A RANDOMIZED PHASE II TRIAL IN PATIENTS WITH OPERABLE STAGE I NON-SMALL CELL LUNG CANCER: RADICAL RESECTION VERSUS ABLATIVE STEREOTACTIC RADIOTHERAPY - This is a Limited Participation Study.

Radiation Therapy Oncology Group·interventional·Posted Dec 20, 2012·Updated Jan 6, 2025

In Brief

A Phase 2 clinical trial evaluating Stereotactic Body Radiation Therapy (SBRT) and Surgery for Non-small Cell Lung Cancer. Targeting 44 participants across 4 sites.

Detailed Summary

Rationale: Surgery remains the standard of care for stage 1 (T1-2a N0)non-small cell lung cancer. Stereotactic body radiation therapy is a newer radiation treatment that gives fewer but higher and possibly more effective doses of radiation than standard radiation. This technique may be able to send x-rays directly to the tumor and cause less damage to normal tissue. It is not yet known whether stereotactic body radiation therapy is more effective than surgery in treating non-small cell lung cancer. Purpose: The primary aim of this randomized phase II trial is to determine if the efficacy of SBRT is comparable to that of standard surgical interventions for patients with T1N0 non-small cell lung cancer.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesChina

Timeline

Phase 2UnknownOverdue
20132014201520162017201820192020202120222023202420252026
First PostedDec 20, 2012
Enrollment StartDec 1, 2012
Primary CompletionApr 3, 2023
Study CompletionJan 1, 2026
TodayJul 2, 2026
Enrollment to primary: 10.3 yearsPosted 13.5 years ago

Interventions

Stereotactic Body Radiation Therapy (SBRT)radiation

Daily fractions

Surgeryprocedure

Radical resection