CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 26 enrolled
Drug / intervention
Colchicine, 0.6 mg PO BID +1 moredrug
Likely dose
Colchicine, 0.6 mg PO BIDfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01755949
NCT01755949Phase 2Completed

Impact and Time Course of Colchicine Therapy on C-reactive Protein Elevation in Chronic Atrial Fibrillation (AF) and Post AF Ablation

Mayo Clinic·interventional·Posted Dec 24, 2012·Updated May 9, 2019

In Brief

A Phase 2 clinical trial evaluating Colchicine, 0.6 mg PO BID and Matching placebo for Atrial Fibrillation. Completed, enrolled 26 participants across 1 site.

Detailed Summary

Colchicine will lower C-reactive protein (CRP) in chronic atrial fibrillation and reduce the rise in CRP which occurs following atrial fibrillation ablation

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
CollaboratorsTakeda, Detiger Funds

Timeline

Phase 2CompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedDec 24, 2012
Enrollment StartMar 1, 2013
Primary CompletionDec 6, 2016
TodayJul 2, 2026
Enrollment to primary: 3.8 yearsPosted 13.5 years ago

Interventions

Colchicine, 0.6 mg PO BIDdrug

Colchicine tablets will be over-encapsulated by the research pharmacy to be indistinguishable from placebo

Matching placebodrug

Matching placebo tablets will be encapsulated by the research pharmacy to be indistinguishable from active drug