CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 80 enrolled
Drug / intervention
Control: Femoral perineural local anesthetic infusion +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01759277
NCT01759277Phase 4Completed

Femoral Versus Adductor Canal Continuous Peripheral Nerve Blocks for Knee Arthroplasty

University of California, San Diego·interventional·Posted Jan 3, 2013·Updated Feb 18, 2021

In Brief

A Phase 4 clinical trial evaluating Control: Femoral perineural local anesthetic infusion and Experimental: Adductor Canal perineural local anesthetic infusion for Postoperative Pain Following Knee Arthroplasty. Completed, enrolled 80 participants across 1 site.

Detailed Summary

Patients typically experience moderate-to-severe pain following knee arthroplasty that is usually treated with a combination of oral and intravenous analgesics and enhanced by continuous peripheral nerve blocks. There are currently two locations to place a perineural catheter to provide analgesia following knee arthroplasty: a femoral nerve catheter and an adductor canal catheter. Both have been demonstrated to be effective following knee arthroplasty. However, it remains unknown if one location is superior to the other; or, more accurately, what the relative benefits are to each technique. While femoral CPNB has many benefits, one of the challenges of using this technique is that there is a decrease in quadriceps muscle strength which can be a limiting factor for rehabilitation. In contrast, the adductor canal catheter affects only the vastus medialis. This block may lessen block-induced quadriceps weakness following knee arthroplasty compared with a femoral infusion. The investigators hypothesize that compared with femoral perineural local anesthetic infusion, an adductor canal infusion is associated with a shorter time until four discharge criteria are met: (1) adequate analgesia; (2) independence from intravenous analgesics; (3) ability to ambulate 30 m; and (4) ability to stand, walk 3 m, and return to a sitting position without another's assistance.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 4CompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedJan 3, 2013
Enrollment StartDec 1, 2012
Primary CompletionSep 1, 2014
TodayJul 2, 2026
Enrollment to primary: 1.8 yearsPosted 13.5 years ago

Interventions

Control: Femoral perineural local anesthetic infusiondrug

The control group will receive a femoral nerve block and postoperative ropivacaine 0.2% infusion

Experimental: Adductor Canal perineural local anesthetic infusiondrug

The control group will receive an adductor canal nerve block and postoperative ropivacaine 0.2% infusion