CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 50 enrolled
Drug / intervention
Aminophylline +2 moredrug
Likely dose
Aminophylline 5mg/kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01759862
NCT01759862N/ACompleted
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Perioperative Aminophylline to Improve High Risk Renal Graft Outcome- a Double Blinded, Placebo Controlled, Randomized Clinical Trial

Stanford University·interventional·Posted Jan 3, 2013·Updated Mar 5, 2019

In Brief

A clinical study evaluating Aminophylline, Theophylline drug levels, and 1 other intervention for Function of Renal Transplant. Completed, enrolled 50 participants across 1 site.

Detailed Summary

The aim of this study is to evaluate whether peri-transplant administration of a drug named aminophylline to children undergoing a kidney transplant from deceased donors improves early graft function and also projects on long term graft function.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsFunction of Renal Transplant
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedJan 3, 2013
Enrollment StartNov 1, 2012
Primary CompletionJan 5, 2017
Study CompletionJul 25, 2017
TodayJul 2, 2026
Enrollment to primary: 4.2 yearsPosted 13.5 years ago

Interventions

Aminophyllinedrug

Aminophylline loading dose 5mg/kg prior to transplant and will continue to receive aminophylline 1.8mg/kg Q6h for a total of 20 doses.

Theophylline drug levelsother

Theophylline drug levels will be monitored every morning from all patients for the first 4 days post- transplant.

Placebodrug

Patients will receive placebo infusion of normal saline, pre-transplant, followed by normal saline infusions matched by volume and frequency to treatment arm for a total of 20 doses.