At a glance
ClinicalIndex Comparison RecordN/ACompleted· 200 enrolled
Drug / intervention
Diphenhydramine +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Randomized Trial of Diphenhydramine Versus Continued Midazolam in "Difficult-to-sedate" Patients Undergoing Colonoscopy
In Brief
A clinical study evaluating Diphenhydramine and Midazolam for Sedation and Endoscopy. Completed, enrolled 200 participants across 1 site.
Detailed Summary
Patients who are undergoing colonoscopy and are not adequately sedated after initial standard sedation with midazolam 5 mg and fentanyl 100 mcg will be randomly assigned to receive diphenhydramine vs. continued midazolam, and their level of sedation will be assessed. Our hypothesis is that diphenhydramine will provide better sedation than continued administration of midazolam during colonoscopy in patients not achieving adequate sedation with standard doses of midazolam plus fentanyl.
Study Details
Timeline
N/ACompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedJan 2013
Enrollment StartFeb 2013
Primary CompletionJun 2015
Study CompletionApr 2016
TodayJul 2026
First PostedJan 16, 2013
Enrollment StartFeb 1, 2013
Primary CompletionJun 1, 2015
Study CompletionApr 1, 2016
TodayJul 2, 2026
Enrollment to primary: 2.3 yearsPosted 13.5 years ago
Interventions
Diphenhydraminedrug
Midazolamdrug