CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 608 enrolled
Drug / intervention
Umeclidinium bromide 62.5mcg +2 moredrug
Likely dose
Umeclidinium bromide 62.5mcgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01772147
NCT01772147Phase 3Completed

A Multicenter, Randomized, Double-blind, Parallelgroup Study to Evaluate the Efficacy and Safety of the Addition of Umeclidinium Bromide Inhalation Powder (62.5mcg) Once-daily to Fluticasone Propionate/Salmeterol (250/50mcg) Twice-daily, Umeclidinium Bromide Inhalation Powder (125mcg) Once-daily to Fluticasone Propionate/Salmeterol (250/50mcg) Twice-daily Versus Placebo to Fluticasone Propionate/Salmeterol (250/50mcg) Twice-daily Over 12 Weeks in Subjects With COPD.

GlaxoSmithKline·interventional·Posted Jan 21, 2013·Updated Mar 23, 2017

In Brief

A Phase 3 clinical trial evaluating Umeclidinium bromide 62.5mcg, Umeclidinium bromide 125mcg, and 1 other intervention for Pulmonary Disease, Chronic Obstructive. Completed, enrolled 608 participants across 55 sites in 5 countries.

Detailed Summary

The purpose of this 12 week study is to evaluate the effects of the addition of umeclidinium bromide (62.5mcg) once-daily to fluticasone propionate (250/50mcg) twice-daily and umeclidinium bromide (125mcg) once-daily to fluticasone propionate (250/50mcg) twice-daily with placebo when added to fluticasone propionate (250/50mcg) twice-daily on lung function, COPD-related health status assessments and safety in COPD subjects.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesChile, Czechia, Poland, South Korea, United States
Collaborators--

Timeline

Phase 3CompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedJan 21, 2013
Enrollment StartJan 1, 2013
Primary CompletionAug 1, 2013
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 13.4 years ago

Interventions

Umeclidinium bromide 62.5mcgdrug

Inhalation powder

Umeclidinium bromide 125mcgdrug

Inhalation powder

Fluticasone propionate 250mcg/Salmeterol 50mcgdrug

Inhalation powder