CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 374 enrolled
Drug / intervention
Albiglutide +5 moredrug
Likely dose
Albiglutide 30 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01777282
NCT01777282Phase 3Completed

A 52-Week, Open-Label, Multicenter Study to Determine the Long Term Safety and Efficacy of Albiglutide in Combination With Monotherapy of Oral Antihyperglycemic Medications in Japanese Patients With Type 2 Diabetes Mellitus

GlaxoSmithKline·interventional·Posted Jan 28, 2013·Updated May 3, 2017

In Brief

A Phase 3 clinical trial evaluating Albiglutide, Sulfonylurea, and 4 other interventions for Diabetes Mellitus. Completed, enrolled 374 participants across 49 sites.

Detailed Summary

This study is designed to examine the long term safety and efficacy of weekly subcutaneously injected albiglutide in combination with a single oral antidiabetic drug for 52 weeks in Japanese subjects with type 2 diabetes mellitus.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesJapan
Collaborators--

Timeline

Phase 3CompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedJan 28, 2013
Enrollment StartFeb 23, 2013
Primary CompletionJan 27, 2015
TodayJul 2, 2026
Enrollment to primary: 1.9 yearsPosted 13.4 years ago

Interventions

Albiglutidedrug

Albiglutide is a fixed-dose, fully disposable pen injector system for delivery of albiglutide from a prefilled dual chamber glass cartridge that is an integral part of the pen. It is intended for single use by the subject. It is designed for manual reconstitution of the dose, priming, and insertion of the pen needle, and manual injection by the subject. The subject will inject albiglutide 30 mg weekly for 52 weeks (with optional uptitration to 50 mg weekly) subcutaneously into the abdomen, alternating between left and right sides. The pen is designed to work with standard pen needles.

Sulfonylureadrug

Single oral antidiabetic drug as a background therapy, to be continued as previously prescribed.

Biguanidedrug

Single oral antidiabetic drug as a background therapy, to be continued as previously prescribed.

Glinidedrug

Single oral antidiabetic drug as a background therapy, to be continued as previously prescribed.

Thiazolidinedionedrug

Single oral antidiabetic drug as a background therapy, to be continued as previously prescribed.

Alpha-glucosidase inhibitordrug

Single oral antidiabetic drug as a background therapy, to be continued as previously prescribed.