CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 236 enrolled
Drug / intervention
SternaLock Blue closure system +1 moredevice
Likely dose
SternaLock Blue closure system (rigid plate-based sternal fixation) versus Suture Wire (wire-based sternal closure)AI-extracted
Key inclusion· 4
  • Patients undergoing full standard midline sternotomy for cardiac surgery (CABG and/or valve replacement with other cardiac procedures)
  • Age ≥18 years
  • BMI <40
  • Hospital admission on day of or day before scheduled surgery
Key exclusion· 11
  • End-stage renal failure on dialysis
  • Severe COPD (FEV1 <50% or home oxygen requirement)
  • Pre-operative narcotic use
  • Chronic steroids, biologic immunosuppressants, or chemotherapy (exception: steroid inhalers for asthma permitted)

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01783483
NCT01783483N/ACompleted

An Evaluation of Rigid Sternal Fixation in Supporting Bone Healing and Improving Postoperative Recovery: A Prospective, Randomized Trial

Zimmer Biomet·interventional·Posted Feb 5, 2013·Updated Sep 8, 2017

In Brief

A clinical study evaluating SternaLock Blue closure system and Suture Wire for Coronary Artery Disease and 2 related conditions. Completed, enrolled 236 participants across 12 sites.

Detailed Summary

The primary objective of this study is to evaluate sternal bone healing following a full median sternotomy versus standard of care for sternal closure with wire cerclage. Additional outcomes on post-operative pain and analgesic usage, patient function and quality of life, and complications will also be collected. A health economics study will also be conducted, in which cost and billing data will be collected from sites participating in this clinical study.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedFeb 5, 2013
Enrollment StartJan 1, 2013
Primary CompletionJun 1, 2015
Study CompletionDec 1, 2016
TodayJul 2, 2026
Enrollment to primary: 2.4 yearsPosted 13.4 years ago

Interventions

SternaLock Blue closure systemdevice

SternaLock Blue closure system is a primary closure system plate-based

Suture Wiredevice

Closure system wire-based used to approximate the two halfs of the sternum following a median sternotomy.