CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 6,629 enrolled
Drug / intervention
Oxygendrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01787110
NCT01787110Phase 3Completed
CompareCT.gov

DETermination of the Role of OXygen in Suspected Acute Myocardial Infarction (DETO2X-AMI) Based on the SWEDEHEART Registry

Karolinska Institutet·interventional·Posted Feb 8, 2013·Updated Dec 11, 2017

In Brief

A Phase 3 clinical trial evaluating Oxygen for Acute Coronary Syndrome and 3 related conditions. Completed, enrolled 6,629 participants across 34 sites.

Detailed Summary

The use of supplemental oxygen in the setting of suspected acute myocardial infarction (AMI) is manifested in international treatment guidelines and established in prehospital and hospital clinical routine throughout the world. However, to date there is no conclusive evidence from adequately designed and powered trials supporting this practice. Existing data is conflicting and failing to clarify the role of supplemental oxygen in AMI. The DETO2X-AMI trial is designed to shed light on this important issue.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAcute Coronary Syndrome, Non-ST Elevation (NSTEMI) Myocardial Infarction, Acute ST Segment Elevation Myocardial Infarction, Angina, Unstable
CountriesSweden
CollaboratorsSwedish Heart Lung Foundation, Swedish Foundation for Strategic Research, The Swedish Research Council

Timeline

Phase 3CompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedFeb 8, 2013
Enrollment StartApr 1, 2013
Primary CompletionDec 30, 2016
TodayJul 2, 2026
Enrollment to primary: 3.7 yearsPosted 13.4 years ago

Interventions

Oxygendrug

see arm description