At a glance
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Reducing CVD Risk in Caregivers: A Brief Behavioral Activation Intervention
In Brief
A clinical study evaluating Pleasant Events Program (PEP) and Information Support (IS) for Depressive Symptoms and Inflammation. Completed, enrolled 100 participants across 1 site.
Detailed Summary
Cardiovascular disease and depression are some of the most costly illnesses to society, and caring for a loved-one with Alzheimer's disease has been associated with increased risk for both depression and cardiovascular disease. Indeed, depressive symptoms have been linked with elevated plasma concentrations of D-dimer and Interleukin-6 (IL-6), both of which are associated with increased risk for cardiovascular disease (CVD). The present research tests a brief behavioral intervention for reducing both depressive symptoms and CVD biomarkers in Alzheimer caregivers. We hypothesize that caregivers receiving a brief Behavioral Activation (BA) therapy will show greater reductions in depressive symptoms and in CVD biomarkers relative to those randomized to a time-equivalent Information and Support (IS) therapy.
Study Details
Timeline
Interventions
Behavioral Activation Therapy
Information-Support (IS) condition consisted of supportive psychotherapy and informational brochures.