CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 319 enrolled / 319 target
Drug / intervention
Breast surgery +2 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01805076
NCT01805076Phase 3CompletedMonitor (2.2/mo)Completion was 13mo ago
CompareCT.gov

Effect of Preoperative Breast MRI on Surgical Outcomes, Costs and Quality of Life of Women With Breast Cancer

Alliance for Clinical Trials in Oncology·interventional·Posted Mar 6, 2013·Updated Jun 26, 2026

In Brief

A Phase 3 clinical trial evaluating Breast surgery, Magnetic resonance imaging, and 1 other intervention for Estrogen Receptor-negative Breast Cancer and 5 related conditions. Completed, enrolled 319 participants across 179 sites.

Signals

Enrolling slower than its timeline implies

Detailed Summary

The purpose of this study is to test whether patients undergoing a breast MRI (magnetic resonance imaging) before breast surgery will have better results after the surgery. Breast tumors are routinely evaluated using mammograms and ultrasound before surgery. This study would like to find out if using MRI in addition to mammography before surgery improves our ability to evaluate tumors and decide what kind of surgery is best for the patient.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsEstrogen Receptor-negative Breast Cancer, Progesterone Receptor-negative Breast Cancer, Stage IA Breast Cancer, Stage IB Breast Cancer, Stage II Breast Cancer, Triple-negative Breast Cancer
CountriesUnited States
CollaboratorsNational Cancer Institute (NCI), American College of Radiology Imaging Network

Timeline

Phase 3CompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedMar 6, 2013
Enrollment StartMay 21, 2014
Primary CompletionMay 27, 2025
TodayJul 2, 2026
Enrollment to primary: 11.0 yearsPosted 13.3 years ago

Arms & Interventions

Arm 1 (control)other

Patients undergo a clinical breast examination and mammography with ultrasound of the breast and regional nodes followed by breast conserving surgery.

Procedure: Breast surgeryProcedure: Mammography
Arm 2 (experimental)experimental

Patients undergo a clinical breast examination, mammography with ultrasound of breast and regional nodes and breast MRI followed by breast conserving surgery or mastectomy.

Procedure: Breast surgeryProcedure: Magnetic resonance imagingProcedure: Mammography

Interventions

Breast surgeryprocedure

Magnetic resonance imagingprocedure

Mammographyprocedure