At a glance
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Obstructive Sleep Apnea and Neurocognitive and Cardiovascular Function in Children With Down Syndrome
In Brief
A clinical study evaluating Continuous positive airway pressure and Sham or placebo continuous positive airway pressure for Down Syndrome and Obstructive Sleep Apnea Syndrome. Completed, enrolled 27 participants across 1 site.
Detailed Summary
Many individuals with Down syndrome (DS) have breathing problems during sleep. This is called obstructive sleep apnea syndrome (OSAS). OSAS is very common in individuals with Down syndrome because of the shape of their face and tongue and because of their low muscle tone. OSAS can cause a lot of health problems including behavioral and learning problems as well as heart problems. The purpose of this research study is to look at the effects of treating OSAS in individuals with Down syndrome with a machine called Continuous Positive Airway Pressure (CPAP). The investigators want to see if treatment of OSAS improves learning, behavior and heart problems.
Study Details
Timeline
Interventions
Continuous positive airway pressure is a machine used with sleep which compresses air delivered via a nasal mask and thus helps stent the airway open.
Sham or placebo CPAP is a machine used instead of therapeutic CPAP. This machine is similar to a therapeutic CPAP machine but has built in leaks and does not deliver pressure. It is not effective in treating OSAS.